Optimal performance of endoscopic retrograde cholangiopancreatography
requires facility with side-viewing endoscopes and consistent
cannulation of the desired duct. Skilled biliary specialists achieve
successful cannulation 95% to 99% of the time while experienced
community endoscopists should reach cannulation rates above 90%. To
achieve these cannulation rates, endoscopists must be prepared to adapt
to all varieties of periampullary anatomy and pathology. Neither a
rigidly defined sequence of accessories nor a progressively random
attack on the papilla will maximize cannulation success, although
complications may increase with these arbitrary approaches. Difficult
access can usually be overcome by using basic anatomic principles to
optimize endoscope position and cannula axis, and by selecting
accessories based upon identified challenges. This article reviews
manipulation of the visual field within the duodenum, means to optimal
axes for cannulation, commonly encountered difficulties in achieving
biliary access, alternative approaches to biliary access when standard
cannulation is difficult, cannulation of the major and minor pancreatic
ducts, and cannulation in patients with surgically altered anatomy.
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